TRiP research group


Dr. Cathrin Rohleder, PhD
Research Administration Manager and Research Fellow

Scientific interests:
Neurobiology and behavioral biology, Molecular Imaging,
Behavioral pharmacology, physiologal and morphological effects of antipsychotics


Academic education:
1999-2006 Diploma program Biology, RWTH Aachen (Diploma thesis: Investigation of auditory post-effects in screech owl (Tyto alba)).
2006-2012 Postgraduate student, University of Cologne - RG Experimental and clinical Neuropsychopharmacology in cooperation with Max-Planck-Institut for neurological research.

2012 "Investigation of behavioral pharmacology and brain metabolism during acut and chronic modulation of the endocannabinoid system in rats.", University of Cologne, Faculty of Mathematics and Natural Sciences
Professional activity:
2006-2009 Postgraduate student, Dept. of Psychiatry and Psychotherapy, University of Cologne
2009-2012 Postgraduate student, Central Institute of Mental Health
2012-2018 Post doc, Central Institute of Mental Health
since 2018 Research Administration Manager and Research Fellow, Brain and Mind Centre, The University of Sydney
  • C. Rohleder, F. Pahlisch, R. Graf, H. Endepols, F. M. Leweke (2019) Differential pharmaceutical preparations of ∆9-tetrahydrocannabinol differentially affect its behavioral effects in rats. Addict Biol ePub ahead
  • F. M. Leweke*, J. K. Mueller*, B. Lange, S. Fritze, C. E. Topor, D. Koethe, C. Rohleder (2018) Role of the endocannabinoid system in the pathophysiology of schizophrenia: Implications for pharmacological interventions. CNS Drugs 32:605-619
  • O. Grimm, M. Löffler, S. Camping, C. Rohleder, F. M. Leweke, H. Flor (2018) Probing the endocannabinoid system in healthy volunteers: cannabidiol alters fronto-striatal resting-state connectivity. Eur Neuropsychopharmacol 28:841-849
  • D. Koethe*, F. Pahlisch*, M. Hellmich*, C. Rohleder, C. Hoyer, A. Meyer-Lindenberg, E. F. Torrey, D. Piomelli, F. M. Leweke (2018) Familial abnormalities of endocannabinoid signalling in schizophrenia. World J Biol Psychiatry, pub ahead
  • F. M. Leweke, C. Rohleder, J. K. Mueller, D. Hirjak, A. Meyer-Lindenberg (2018) Cannabidiol zur Verbesserung der Genesung in frühen Stadien einer Schizophrenie. Eine randomisierte, kontrollierte klinische Prüfung der adjuvanten Gabe zur individuellen antipsychotischen Behandlung. Nervenheilkunde 37:1-4
  • C. Rohleder*, D. Koethe*, S. Fritze, C. E. Topor, F. M. Leweke, D. Hirjak (2018) Neural correlates of binocular depth inversion illusion in antipsychotic-naïve first-episode schizophrenia patients. Eur Arch Psychiatry Clin Neurosci DOI 10.1007/s00406-018-0886-2
  • A. R. Reuter*, J. M. Bumb*, J. K. Mueller*, C. Rohleder, F. Pahlisch, F. Hanke, E. Arens, F. M. Leweke, D. Koethe#, E. Schwarz# (2017) Association of anandamide with altered binocular depth inversion illusion in schizophrenia. World J Biol Psychiatry 18:483-48
  • C. Rohleder, D. Wiedermann, B. Neumaier, A. Drzezga, L. Timmermann, R. Graf, F. M. Leweke, Heike Endepols (2016) The functional networks of prepulse inhibition: Neuronal connectivity analysis based on FDG-PET in awake and unrestrained rats. Front Behav Neurosci, 7:422
  • F. M. Leweke, J. K. Mueller, B. Lange, C. Rohleder (2016) Therapeutic potential of cannabinoids in psychosis. Biol Psychiatry 79:604-612
  • J. K. Mueller, C. Rohleder, F. M. Leweke (2016) What is the promise of nicotinergic compounds in schizophrenia treatment? Future Med Chem 8:2009-2012
  • E. G. Severance, K. L. Gressitt, A. Alaedini, C. Rohleder, F. Enning, J. M. Bumb, J. K. Mueller, E. Schwarz, R. H. Yolken, F. M. Leweke (2015) IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia. Brain Behav Immun 44, 148-58.
  • M. Grosshans, E. Schwarz, J. M. Bumb, C. Schaefer, C. Rohleder, C. Vollmert, S. Vollstadt-Klein, H. Tost, A. Meyer-Lindenberg, F. Kiefer, F. M. Leweke (2014) Oleoylethanolamide and human neural responses to food stimuli in obesity. JAMA Psychiatry 71, 1254-61.
  • C. Rohleder, F. Jung, H. Mertgens, D. Wiedermann, M. Sue, B. Neumaier, R. Graf, F. M. Leweke, H. Endepols (2014) Neural correlates of sensorimotor gating: a metabolic positron emission tomography study in awake rats. Front Behav Neurosci 8, 178.
  • C. Schaefer, F. Enning, J. K. Mueller, J. M. Bumb, C. Rohleder, T. M. Odorfer, J. Klosterkotter, M. Hellmich, D. Koethe, C. Schmahl, M. Bohus, F. M. Leweke (2014) Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. Eur Arch Psychiatry Clin Neurosci 264:459-463.
  • European Network of National Networks studying Gene-Environment Interactions in, J. van Os, B. P. Rutten, I. Myin-Germeys, P. Delespaul, W. Viechtbauer, C. van Zelst, R. Bruggeman, U. Reininghaus, C. Morgan, R. M. Murray, M. Di Forti, P. McGuire, L. R. Valmaggia, M. J. Kempton, C. Gayer-Anderson, K. Hubbard, S. Beards, S. A. Stilo, A. Onyejiaka, F. Bourque, G. Modinos, S. Tognin, M. Calem, M. C. O'Donovan, M. J. Owen, P. Holmans, N. Williams, N. Craddock, A. Richards, I. Humphreys, A. Meyer-Lindenberg, F. M. Leweke, H. Tost, C. Akdeniz, C. Rohleder, J. M. Bumb, E. Schwarz et al. (2014) Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. Schizophr Bull 40, 729-36.
  • L. N. Hayes, E. G. Severance, J. T. Leek, K. L. Gressitt, C. Rohleder, J. M. Coughlin, F. M. Leweke, R. H. Yolken, A. Sawa (2014) Inflammatory molecular signature associated with infectious agents in psychosis. Schizophr Bull 40, 963-72.