TRiP research group

TRiP

Dr. Cathrin Rohleder, PhD
Post doc, Head of Lab

Scientific interests:
Neurobiology and behavioral biology, Molecular Imaging,
Behavioral pharmacology, physiologal and morphological effects of antipsychotics

cathrin_joepen

Academic education:
1999-2006 Diploma program Biology, RWTH Aachen (Diploma thesis: Investigation of auditory post-effects in screech owl (Tyto alba)).
2006-2012 Postgraduate student, University of Cologne - RG Experimental and clinical Neuropsychopharmacology in cooperation with Max-Planck-Institut for neurological research.

Dissertation:
2012 "Investigation of behavioral pharmacology and brain metabolism during acut and chronic modulation of the endocannabinoid system in rats.", University of Cologne, Faculty of Mathematics and Natural Sciences
 
Professional activity:
2006-2009 Postgraduate student, Dept. of Psychiatry and Psychotherapy, University of Cologne
2009-2012 Postgraduate student, Central Institute of Mental Health
2012-2018 Post doc, Central Institute of Mental Health
since 2018 Research Administration Manager and Research Fellow, Brain and Mind Centre, The University of Sydney
 
Publications:
  • F. M. Leweke*, J. K. Mueller*, B. Lange, S. Fritze, C. E. Topor, D. Koethe, C. Rohleder (2018) Role of the endocannabinoid system in the pathophysiology of schizophrenia: Implications for pharmacological interventions. CNS Drugs 32:605-619
  • O. Grimm, M. Löffler, S. Camping, C. Rohleder, F. M. Leweke, H. Flor (2018) Probing the endocannabinoid system in healthy volunteers: cannabidiol alters fronto-striatal resting-state connectivity. Eur Neuropsychopharmacol 28:841-849
  • D. Koethe*, F. Pahlisch*, M. Hellmich*, C. Rohleder, C. Hoyer, A. Meyer-Lindenberg, E. F. Torrey, D. Piomelli, F. M. Leweke (2018) Familial abnormalities of endocannabinoid signalling in schizophrenia. World J Biol Psychiatry, pub ahead
  • F. M. Leweke, C. Rohleder, J. K. Mueller, D. Hirjak, A. Meyer-Lindenberg (2018) Cannabidiol zur Verbesserung der Genesung in frühen Stadien einer Schizophrenie. Eine randomisierte, kontrollierte klinische Prüfung der adjuvanten Gabe zur individuellen antipsychotischen Behandlung. Nervenheilkunde 37:1-4
  • C. Rohleder*, D. Koethe*, S. Fritze, C. E. Topor, F. M. Leweke, D. Hirjak (2018) Neural correlates of binocular depth inversion illusion in antipsychotic-naïve first-episode schizophrenia patients. Eur Arch Psychiatry Clin Neurosci DOI 10.1007/s00406-018-0886-2
  • A. R. Reuter*, J. M. Bumb*, J. K. Mueller*, C. Rohleder, F. Pahlisch, F. Hanke, E. Arens, F. M. Leweke, D. Koethe#, E. Schwarz# (2017) Association of anandamide with altered binocular depth inversion illusion in schizophrenia. World J Biol Psychiatry 18:483-48
  • C. Rohleder, D. Wiedermann, B. Neumaier, A. Drzezga, L. Timmermann, R. Graf, F. M. Leweke, Heike Endepols (2016) The functional networks of prepulse inhibition: Neuronal connectivity analysis based on FDG-PET in awake and unrestrained rats. Front Behav Neurosci, 7:422
  • F. M. Leweke, J. K. Mueller, B. Lange, C. Rohleder (2016) Therapeutic potential of cannabinoids in psychosis. Biol Psychiatry 79:604-612
  • J. K. Mueller, C. Rohleder, F. M. Leweke (2016) What is the promise of nicotinergic compounds in schizophrenia treatment? Future Med Chem 8:2009-2012
  • E. G. Severance, K. L. Gressitt, A. Alaedini, C. Rohleder, F. Enning, J. M. Bumb, J. K. Mueller, E. Schwarz, R. H. Yolken, F. M. Leweke (2015) IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia. Brain Behav Immun 44, 148-58.
  • M. Grosshans, E. Schwarz, J. M. Bumb, C. Schaefer, C. Rohleder, C. Vollmert, S. Vollstadt-Klein, H. Tost, A. Meyer-Lindenberg, F. Kiefer, F. M. Leweke (2014) Oleoylethanolamide and human neural responses to food stimuli in obesity. JAMA Psychiatry 71, 1254-61.
  • C. Rohleder, F. Jung, H. Mertgens, D. Wiedermann, M. Sue, B. Neumaier, R. Graf, F. M. Leweke, H. Endepols (2014) Neural correlates of sensorimotor gating: a metabolic positron emission tomography study in awake rats. Front Behav Neurosci 8, 178.
  • C. Schaefer, F. Enning, J. K. Mueller, J. M. Bumb, C. Rohleder, T. M. Odorfer, J. Klosterkotter, M. Hellmich, D. Koethe, C. Schmahl, M. Bohus, F. M. Leweke (2014) Fatty acid ethanolamide levels are altered in borderline personality and complex posttraumatic stress disorders. Eur Arch Psychiatry Clin Neurosci 264:459-463.
  • European Network of National Networks studying Gene-Environment Interactions in, J. van Os, B. P. Rutten, I. Myin-Germeys, P. Delespaul, W. Viechtbauer, C. van Zelst, R. Bruggeman, U. Reininghaus, C. Morgan, R. M. Murray, M. Di Forti, P. McGuire, L. R. Valmaggia, M. J. Kempton, C. Gayer-Anderson, K. Hubbard, S. Beards, S. A. Stilo, A. Onyejiaka, F. Bourque, G. Modinos, S. Tognin, M. Calem, M. C. O'Donovan, M. J. Owen, P. Holmans, N. Williams, N. Craddock, A. Richards, I. Humphreys, A. Meyer-Lindenberg, F. M. Leweke, H. Tost, C. Akdeniz, C. Rohleder, J. M. Bumb, E. Schwarz et al. (2014) Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations. Schizophr Bull 40, 729-36.
  • L. N. Hayes, E. G. Severance, J. T. Leek, K. L. Gressitt, C. Rohleder, J. M. Coughlin, F. M. Leweke, R. H. Yolken, A. Sawa (2014) Inflammatory molecular signature associated with infectious agents in psychosis. Schizophr Bull 40, 963-72.